Kerala PSC has called for Scientific officer post in the Department of Police Forensic Laboratories. The syllabus for Physics Subject candidates are as follows. Download kerala PSC Scientific officer syllabus for physics at the end of this page.
MODULE I: SYSTEMATICS AND EVOLUTIONARY BIOLOGY
1. SYSTEMATICS
• Basic concepts , Importance and applications
• Trends -Chemotaxonomy, Cytotaxonomy, Molecular taxonomy, Cladistics, Numerical taxonomy
• Dimensions of speciation, Species concept, Theories of biological classification, Hierarchy of categories.
• Procedural keys- Taxonomic procedures- Collection, Preservation, Curating, Identification.
• Taxonomic keys- Merits and demerits; ICZN, Formation of scientific names of various taxa.
2. EVOLUTIONARY BIOLOGY
An outline of evolutionary theories: Darwinism, Lamarckism, Modern synthesis (not in detail).
Origin of higher categories- Punctuated equilibrium- Macroevolution Microevolution Coevolution-Founder principle- C-value paradox-Concept of molecular clock Cytochrome C- Haemoglobin-Histone.
MODULE II: PHYSIOLOGY AND BIOCHEMISTRY.
I. PHYSIOLOGY
1. Nutrition and Digestion
• Types of nutrition
• Mechanism of Digestion , Absorption
• Gastrointestinal hormones
• Deficiency diseases of nutrients.
2. Circulatory Physiology
• Physiology of cardiac muscles
• cardiac cycle
• Electrical properties
• conducting system of heart
• Blood pressure
• Blood volume
• pressure control - integrated system.
3. Nerve Physiology
• Nerve action potential
• conduction of nerve impulse
• Synapse
• Synaptic transmission
• Neurotransmitters.
4. Excretory physiology
5. Respiratory physiology
6. Muscle physiology
7. Endocrinology
• Major Endocrine glands and their hormones and functions
• Mechanism of hormone action.
II. BIOCHEMISTRY
Biomolecules
• Carbohydrates: Classification, Structure, Properties, Functions.
• Proteins: Classification, Structure, Properties, Functions.
• Lipids: Classification, Structure, Properties, functions.
Enzymes: Mechanism of enzyme action. Factors affecting enzyme action, Enzyme kinetics,
Menten Michaelis kinetics, Substrate concentration, Enzyme inhibition and regulation, Isozyme,
Coenzyme, Ribozymes.
Metabolism of carbohydrate: Glycolysis, TCA cycle, Pentose phosphate pathway, Glycogenesis,
Gluconeogenesis, Gluconeogenesis, Regulation of carbohydrate metabolism.
Metabolism of protein: Deamination, Transamination,
Metabolism of Lipids: B oxidation, Synthesis of Fatty acid, Biosynthesis of cholesterol.
Energy metabolism: Oxidative metabolism, Oxidative phosphorylation, Chemiosmotic theory
MODULE III: MICROBIOLOGY AND IMMUNOLOGY
I. MICROBIOLOGY
• Classification of Microorganisms- Berg's manual.
• Salient features of Bacteria, Viruses, Fungi, Protozoa, Algae.
• Bacterial Cell- Structure and function
• Bacterial Cell wall- Peptidoglycan, Gram's positive and Gram's negative, Mechanism of Gram's
staining.
• Bacterial culture media
• Growth curves
2. Industrial Microbiology: Fermentation.
II: IMMUNOLOGY
• Types of immunity - Innate, Acquired, Passive, Active, Cell mediated.
• Cells of primary and secondary lymphoid organs.
• Cells and organs of immune system.
III. Immunogens [ Antigen]
• General properties- Structure and function, Variability and Diversity.
• Factors affecting antigenicity
• Epitopes and haptens
• Adjuvants.
IV. Immunoglobulins [Antibodies]
• General properties- Structure and function
• Different classes- Ig A, IgD, IgE, IgM
• Variability and Diversity
• Monoclonal and polyclonal antibodies
V. Antigen Antibody interaction
Complement system- Classical pathway, Alternate, cell mediated and humoral reactions.
VI. Transplantation
MHC genes, Auto-immune diseases.
• MODULE IV CELL, MOLECULAR BIOLOGY AND BIOTECHNOLOGY
CELL
Cell membrane- Structure and function.
Cell organelles with special reference to Mitochondria and Ribosomes
MOLECULAR BIOLOGY
• Organization of eukaryotic genome, gene content and genomic size complexity of eukaryotic
genome, conserved exons and recombination
• DNA replication, Repair and Recombination
• Prokaryotic and eukaryotic DNA replication. Enzyme involved in replication. DNA damage and
repair.
• Transcription and RNA processing
• Prokaryotic and Eukaryotic transcription, Binding of transcription complexes, Post -
transcriptional processing
• Translation- prokaryotic and eukaryotic gene expression, Translational machinery, mechanism
of initiation, elongation and termination, Post-translational modification of protein.
• Gene regulation mechanism in Prokaryotes, Eukaryotes
• Transcriptional signals-TATA, CAAT box, Enhancers.
A. BIOTECHNOLOGY
Gene cloning.
• Major steps in cloning, Isolation and purification of genes.
• Vectors- properties of an ideal vector, different types [ plasmids, Ti plasmid, bacteriophages,
cosmids, phagemids, artificial chromosomes].
• Enzymes in gene cloning.
• Probes and molecular markers [RFLP, RAPD, AFLP].
• Homopolymer tailing, linkers and adapters. Genetic engineering techniques.
B1 Polymerase Chain reaction, DNA finger printing, Blotting techniques [ Northern, Southern ,
Western blottings, Dot blot, Slot blot].
B2 DNA sequencing - Maxam-Gilbert method, Sanger-Coulson method. Chromosome jumping,
Genomic library and cDNA library, Site specific mutagenesis and gene targeting,
Human genome project, Human gene therapy, and other genome projects. B3 Transgenic
animals.
MODULE V: GENETICS AND DEVELOPMENTAL BIOLOGY
I. GENETICS.
• Mendelian principles of genetics- Laws , Linkage, Crossing over, Mutation, DNA, Types of DNA,
RNA, Types of RNA.
• Lyon hypothesis.
• Syndromes- Klinefelter, Down, Turner.
• Genetic code.
II. DEVELOPMENTAL BIOLOGY
• Gametogenesis, Fertilization and early development - Cleavage, Blastulation, gastrulation,
Organogeny.
• Experimental Embryology.
• Embryonic induction.
MODULE VI: ECOLOGY, ETHOLOGY , BIODIVERSITY CONSERVATION AND
BIOSTATISTICS
1. ECOLOGY:
Definitions- Habit and habitat, Ecological niche, Ecosystem, Population ecology, Community
ecology, Ecological succession, Pollution, Global warming.
2.ETHOLOGY
Learning behaviour, Communication behaviour, Motivation.
3.BIODIVERSITY CONSERVATION
Biodiversity concept, status in India, Value, Loss and causes of loss.
Indices, Hot spots of Biodiversity. In situ and Ex-situ conservation.
4.BIOSTATISTICS
Mean, Median, Mode, Standard deviation; Graphical representation of data.
BIOPHYSICS, BIOINFORMATICS AND COMPUTER APPLICATION
1. INSTRUMENTATION
• Scanning electron microscope, Transmission electron microscope
• Electrophoresis- Gel, PAGE, Agarose, 2D- Immunoelectrophoresis, Fluorescent
• HPLC, Flow cytometry
• NMR spectroscopy- Mass, Plasma , Atomic
• X-ray diffraction
• ELISA
2. BIOINFORMATICS
Proteomics, Genomics, Data bases - Primary and Secondary, Search engines.
Transgenic animals, Stem cell research, IPR, Carbon trading, Ecological foot printing, Treaties
and protocols related to climate change.
MODULE – VII
Recent developments in Zoology
Download this Zoology syllabus as pdf/download/button
View the Tier-1 General Paper syllabus for Scientific Officer/preview/button
